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Genomic Science Program

Systems Biology for Energy and the Environment

Department of Energy Office of Science. Click to visit main DOE SC site.

Genomic Science Program

All Awardee Workshops

Genomics:GTL Contractor—Grantee Workshop IV
Metabolic Engineering Working Group Inter-Agency Conference on Metabolic Engineering 2006

North Bethesda, Maryland
February 12-15, 2006

This is the first Genomics:GTL workshop for principal investigators since the release of Genomics:GTL Roadmap: Systems Biology for Energy and Environment in October 2005 ( Abstracts and posters for this workshop are organized around the GTL goal and milestones shown below and in the roadmap on pp. 42–55. Many of the research projects are essentially pilots or proof-of-principle studies for systems biology, technology and methods development, computing, and facilities.

Most computing abstracts, instead of comprising a separate category, are associated with appropriate experimental topics. Overarching computing infrastructure and education abstracts are under Milestone 3, GTL Computational Biology Environment.

Abstracts of the Metabolic Engineering Working Group (MEWG), an interagency approach to understanding and using metabolic processes, are identified as such and intermixed with GTL abstracts in relevant program categories.

Genomics:GTL Overarching Scientific Goal

Achieve a predictive, systems-level understanding of biological systems to help enable biobased solutions to DOE mission challenges.

Book PDFs: faster download PDF, 4160 kb; higher resolution PDF, 37,939 kb.

Science and Technology Milestones

Milestone 1: The Code—Understand Gene Structure and Functional Potential of Plants and Microbes and Their Communities

  • Organism Sequencing, Annotation, and Comparative Genomics (PDF, 432 kb)
  • Microbial-Community Sequencing (PDF, 213 kb)
  • Protein Production and Characterization (PDF, 330 kb)
  • Molecular Interactions (PDF, 515 kb)

Milestone 2: The Response—Understand Function, Regulation, and Dynamics in Plants and Microbes and Their Communities

  • Omics: Systems Measurements of Plants, Microbes and Communities (PDF, 1951 kb)
  • Metabolic Network Experimentation and Modeling (PDF, 473 kb)
  • Regulatory Processes (PDF, 351 kb)

Milestone 3: GTL Computational Biology Environment

  • Computing Infrastructure and Education (PDF, 122 kb)

Communication (PDF, 89 kb)

Ethical, Legal, and Societal Issues (PDF, 125 kb)

Table of Contents and Welcome (PDF, 533 kb)

Participants (PDF, 73 kb)

Web Sites (PDF, 65 kb)

Indexes (PDF, 124 kb)

Addendum (PDF, 150 kb)

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